Background The use of lengthy, detailed, and complex informed consent forms is of paramount concern in biomedical research as it may not truly promote the rights and interests of research participants. The extent of information in ICFs has been the subject of debates for decades; however, no clear guidance is given. Thus, the objective of this study was to determine the perspectives of research participants about the type and extent of information they need when they are invited to participate in (...) biomedical research. Methods This multi-center, cross-sectional, descriptive survey was conducted at 54 study sites in seven Asia-Pacific countries. A modified Likert-scale questionnaire was used to determine the importance of each element in the ICF among research participants of a biomedical study, with an anchored rating scale from 1 to 5. Results Of the 2484 questionnaires distributed, 2113 were returned. The majority of respondents considered most elements required in the ICF to be ‘moderately important’ to ‘very important’ for their decision making. Major foreseeable risk, direct benefit, and common adverse effects of the intervention were considered to be of most concerned elements in the ICF. Conclusions Research participants would like to be informed of the ICF elements required by ethical guidelines and regulations; however, the importance of each element varied, e.g., risk and benefit associated with research participants were considered to be more important than the general nature or technical details of research. Using a participant-oriented approach by providing more details of the participant-interested elements while avoiding unnecessarily lengthy details of other less important elements would enhance the quality of the ICF. (shrink)

Deinde qui minus grauis esset iis senectus, si octingentesimum annum agerent quam [si] octogesimum ? This sentence has to do with people who complain that the evils of old age have come upon them all too soon. Cicero rejoins that they would be of exactly the same mind, even though they had a life ten times as long to look back upon.

Sentences of the form si sit … esset crop out at rare intervals in the literature of classical Latin, deviating so sharply from what might be called the standard forms of conditional speaking that they have commonly been regarded with more or less suspicion.

The discussion of the construction with usus est is conventionally bound up with that of opus est, and comparatively little attention has been given to the problem presented by the use of the ablative case with the former phrase. The tendency to pass lightly over this matter is due doubtless to the manifest etymological connexion between usus and utor, which leads to the assumption that the verbal noun would naturally follow the syntax of the verb.

In a note on this passage as far back as 1868, E. Wölmin 1 advanced the theory that the plural anulis is used here in a technical and stereotyped way as symbolic of equestrian rank. He is not sure whether such illogical use of the plural is to be found earlier than Tacitus or not.

Truth in the Making represents a sophisticated effort to map the complex relations between human knowledge and creative power, as reflected across more than half a millennium of philosophical enquiry. Showing the intimacy of this problematic to the work of Nicholas of Cusa, Bacon, Galileo, Descartes, Hobbes, Leibniz, Vico and David Lachterman, the book reveals how questions about creation apparently diluted by secularism in fact retain much of their potency today. If science could counterfeit or synthesize nature precisely from its (...) smallest nuts and bolts, as Descartes and Hobbes implied and as modern science increasingly suggests, would it create an identical world to that we live in now Robert C. Miner offers a precise genealogy of modern thought on truth and creation: from medieval theology's identification of human creativity with divine initiative to the radical Leibnizian contention that human ideas are 'not little copies of God's', and may at once exceed mimesis and produce things new, unpredictable and unseen. He considers how the theological importance given to creation interacts historically with the secularisation and instrumentalisation of modes of discovery and method, and asks how knowledge is understood between different disciplines, from the allegorical discipline of poetry to the constructible field of mathematics. The book is an eloquent reminder of the ways in which theology continues to fling a wild card at philosophical understandings of reality, countering theories of metaphysical equivalence of the 'real' and 'artificial' with theologies in which human making is always fallible, and strives only for approximate participation in divine truth. As a strenuous and informative breakdown of leading theories of knowledge, Truth in the Making shows the continuing influence of theological questions upon philosophical, scientific and aesthetic disciplines, whilst raising topical questions about the ultimate nature of our reality and our freedom to modify and define it. (shrink)

This article reconstructs the complex diplomatic negotiations that led to the peculiar organization of molecular biology at the European level, by focusing in particular on the establishment of the European Molecular Biology Conference (EMBC), the intergovernmental structure founded in 1969–70 to support the scientific program of the European Molecular Biology Organization (EMBO). By combining the analysis of the informal decision-making kept in the Nobel Prize laureate John C. Kendrew’s personal papers (Oxford) with the in-depth exploration of the institutional documentation available (...) in the EMBO and CERN archives (Heidelberg and Geneva) and the Swiss Federal Archives (Bern), the article sheds light on the importance of the EMBC not only for the construction of molecular biology as a scientific, social, and political field in the European context, but also for the broader process of definition of the European research policy. Far from being just a mere replica of CERN, the EMBO/EMBC inaugurated in fact an alternative and flexible ‘bottom-up’ model of science policy in the European context, based on competition, networking, and scientific excellence, which paved the way to the establishment of the European Research Council (ERC) in the early 2000s. (shrink)

The philosophical theory of scientific explanation proposed here involves a radically new treatment of causality that accords with the pervasively statistical character of contemporary science. Wesley C. Salmon describes three fundamental conceptions of scientific explanation--the epistemic, modal, and ontic. He argues that the prevailing view is untenable and that the modal conception is scientifically out-dated. Significantly revising aspects of his earlier work, he defends a causal/mechanical theory that is a version of the ontic conception. Professor Salmon's theory furnishes a robust (...) argument for scientific realism akin to the argument that convinced twentieth-century physical scientists of the existence of atoms and molecules. To do justice to such notions as irreducibly statistical laws and statistical explanation, he offers a novel account of physical randomness. The transition from the "reviewed view" of scientific explanation to the causal/mechanical model requires fundamental rethinking of basic explanatory concepts. (shrink)

Stať se snaží analyzovat myšlenky málo známého rukopisu Sigmunda Freuda z roku 1895, v němž usiloval o nalezení biologických základů lidské psychiky. Tato práce je pozoruhodná ze dvou důvodů. Jednak představuje úvahy, které se výrazně od- lišují od toho, co je pro Freuda v oblasti psychologie tak typické. Freud se zde, až na výjimky, nezabývá psychoanalýzou či studiemi o hysterii, nýbrž popisuje, co by mohlo být základem těchto psychologických jevů na neurofyziologické úrovni. Druhým pozoruhodným faktem je, že tento manuskript byl (...) pozapome- nut až do poloviny 20. století, kdy byl vytištěn pod názvem Projekt vědecké psychologie. A jak je známo, neurofyziologická studia lidské mysli spojená s analýzou kognitivních funkcí se v ri- gorózní podobě objevují až na počátku 60. let. Stať se proto pokouší ukázat základní principy Projektu a naznačit, v čem byl Freud inspirativním průkopníkem moderních neurofyziologických přístupů k lidské mysli. (shrink)

This classic and controversial book examines the roots of the idea of virtue, diagnoses the reasons for its absence in modern life, and proposes a path for its recovery.

_Rhetoric_ is the sixth volume in The New Hackett Aristotle series, a series featuring translations, with Introductions and Notes, by C. D. C. Reeve, Delta Kappa Epsilon Distinguished Professor of Philosophy at The University of North Carolina at Chapel Hill. The series will eventually include all of Aristotle's works.

Investigates the resolution of contradictions and ambiguous derogations in a code, by means of the imposition of partial orderings. Although formulated as a study in the logic of norms, it provided the initial ideas for work on the logic of theory (or belief) change, developed by the authors in a series of papers by the authors and Peter Gardenfors beginning in 1985.

Aristotle's treatise De Interpretatione is one of his central works; it continues to be the focus of much attention and debate. C. W. A. Whitaker presents the first systematic study of this work, and offers a radical new view of its aims, its structure, and its place in Aristotle's system, basing this view upon a detailed chapter-by-chapter analysis.By treating the work systematically, rather than concentrating on certain selected passages, Whitaker is able to show that, contrary to traditional opinion, it forms (...) an organized and coherent whole. He argues that the De Interpretatione is intended to provide the underpinning for dialectic, the system of argument by question and answer set out in Aristotle's Topics; and he rejects the traditional view that the De Interpretatione concerns the assertion and is oriented towards the formal logic of the Prior Analytics. In doing so, he sheds valuable new light on some of Aristotle's most famous texts. (shrink)

'Original and provocative . . . engagingly written. (C Fred Alford) counters Levinas's notorious obscurity with a goodly dose of transparency' - John Lechte, Macquarrie University Abstract and evocative, writing in what can only be ...

"This edition, which replaces the original Loeb edition..., offers text, translation, and annotation that are fully current with modern scholarship"--Front flap of dust jacket, volume 1.

C. Stephen Evans explains and defends Kierkegaard's account of moral obligations as rooted in God's commands, the fundamental command being `You shall love your neighbour as yourself'. The work will be of interest not only to those interested in Kierkegaard, but also to those interested in the relation between ethics and religion, especially questions about whether morality can or must have a religious foundation. As well as providing a comprehensive reading of Kierkegaard as an ethical thinker, Evans puts him into (...) conversation with contemporary moral theorists. Kierkegaard's divine command theory is shown to be an account that safeguards human flourishing, as well as protecting the proper relations between religion and state in a pluralistic society. (shrink)

_Verificationism_ is the first comprehensive history of a concept that dominated philosophy and scientific methodology between the 1930s and the 1960s. The verificationist principle - the concept that a belief with no connection to experience is spurious - is the most sophisticated version of empiricism. More flexible ideas of verification are now being rehabilitated by a number of philosophers. C.J. Misak surveys the precursors, the main proponents and the rehabilitators. Unlike traditional studies, she follows verificationist theory beyond the demise of (...) positivism to examine its reappearance in the work of modern philosophers. Most interestingly, she argues that despite feminism's strenuous opposition to positivism, verificationist thought is at the heart of much of contemporary feminist philosophy. _Verificationism_ is an excellent assessment of a major and influential system of thought. (shrink)

Is there such a thing as natural knowledge of God? C. Stephen Evans presents the case for understanding theistic arguments as expressions of natural signs in order to gain a new perspective both on their strengths and weaknesses. Three classical, much-discussed theistic arguments - cosmological, teleological, and moral - are examined for the natural signs they embody. At the heart of this book lie several relatively simple ideas. One is that if there is a God of the kind accepted by (...) Christians, Jews, and Muslims, then it is likely that a 'natural' knowledge of God is possible. Another is that this knowledge will have two characteristics: it will be both widely available to humans and yet easy to resist. If these principles are right, a new perspective on many of the classical arguments for God's existence becomes possible. We understand why these arguments have for many people a continued appeal but also why they do not constitute conclusive 'proofs' that settle the debate once and for all. Touching on the interplay between these ideas and contemporary scientific theories about the origins of religious belief, particularly the role of natural selection in predisposing humans to form beliefs in God or gods, Evans concludes that these scientific accounts of religious belief are fully consistent, even supportive, of the truth of religious convictions. (shrink)

"A rich collection. Since it holds a number of introductory pieces along with advanced essays and review articles, the volume will be accessible to a broad audience and will work well in philosophy of science courses....Essential."--Lawrence Sklar, University of Michigan.

A critical and detailed introduction to Kant's philosophy, with particular reference to the Critique of Pure Reason. Since Broad's death there have been many publications on Kant but Broad's 1978 book still finds a definite place between the very general surveys and the more specialised commentaries. He offers a characteristically clear, judicious and direct account of Kant's work; his criticisms are acute and sympathetic, reminding us forcefully that 'Kant's mistakes are usually more important than other people's correctitudes'. C.D. Broad was (...) Knightsbridge Professor of Moral Philosophy at Cambridge from 1933 to 1953, and this book is based on his undergraduate lectures on Kant. Broad died in 1971 and Dr Lewy has since edited the book for publication. (shrink)

In this investigation of the contemporary notion of evil, C. Fred Alford asks what we can learn about this concept, and about ourselves, by examining a society where it is unknown--where language contains no word that equates to the English term "evil." Does such a society look upon human nature more benignly? Do its members view the world through rose-colored glasses? Korea offers a fascinating starting point, and Alford begins his search for answers there.In conversations with hundreds of Koreans from (...) diverse religions and walks of life--students, politicians, teachers, Buddhist monks, Confucian scholars, Catholic priests, housewives, psychiatrists, and farmers--Alford found remarkable agreement about the nonexistence of evil. Koreans regard evil not as a moral category but as an intellectual one, the result of erroneous Western thinking. For them, evil results from the creation of dualisms, oppositions between people and ideas.Alford's interviews often led to discussions about imported ways of thinking and the impact of globalization upon society at large. In particular, he was struck by how Koreans' responses to globalization matched Westerners' views about evil. In much of the world, he argues, globalization is the ultimate dualism--attractive for the enlightenment and freedom it brings, terrifying for the great social and personal upheaval it can cause. (shrink)

The self is a topic that crosses a great many disciplinary boundaries; concepts of the self are central to political science, psychoanalysis, philosophy, sociology, and classical studies. In this book, C.Fred Alford sets forth a psychoanalytic account of the self and applies it to texts by Plato, Hobbes, Locke, Rawis, and Rouseau in order to draw out their implicit, often inchoate, assumptions about the self.

The Holocaust marks a decisive moment in modern suffering in which it becomes almost impossible to find meaning or redemption in the experience. In this study, C. Fred Alford offers a new and thoughtful examination of the experience of suffering. Moving from the Book of Job, an account of meaningful suffering in a God-drenched world, to the work of Primo Levi, who attempted to find meaning in the Holocaust through absolute clarity of insight, he concludes that neither strategy works well (...) in today's world. More effective are the day-to-day coping practices of some survivors. Drawing on testimonies of survivors from the Fortunoff Video Archives, Alford also applies the work of Julia Kristeva and the psychoanalyst Donald Winnicot to his examination of a topic that has been and continues to be central to human experience. (shrink)

Most whistleblowers talk as if they never had a choice about whether to blow the whistle. This doesn't mean they acted suddenly, or impulsively, only that they believe they could not have done otherwise. Trying to make sense of this near universal answer to the question "Why did you do it?" the essay draws on narrative theory. Narrative theory distinguishes between actant and sender—that is, between actor and his or her values. This distinction helps to explain what it means to (...) face a difficult choice over something about which one feels one never had a choice. (shrink)

Part of the draw of athletics is its straightforwardness. There are nuances to competitions to make them more sporting contests, but at the end of a long jump competition whomever records the longest jump should win. Unfortunately, a recent rule-change at the highest level of the sport – the “Final 3” format – undermined this simplicity for the horizontal jumps and the throws for some of the 2020 and much of the 2021 seasons. While fortunately this rule was largely reverted (...) within days of the initial submission of this paper, it’s still valuable to critically evaluate why such a rule is problematic so as to better understand of the value of sporting competitions and give guidance on future rule changes, be they in athletics or other sports. To that end, we will be drawing from the literature on the purpose and value of competitions and coupling that with simulations based on data from actual top-tier long jump competitions to show that the Final 3 format makes for significantly worse competitions than the standard format. (shrink)

C. Stephen Evans provides a clear, readable introduction to Søren Kierkegaard (1813–55) as a philosopher and thinker. His book is organised around Kierkegaard's concept of the three 'stages' or 'spheres' of human existence, which provide both a developmental account of the human self and an understanding of three rival views of human life and its meaning. Evans also discusses such important Kierkegaardian concepts as 'indirect communication', 'truth as subjectivity', and the Incarnation understood as 'the Absolute Paradox'. Although his discussion emphasises (...) the importance of Christianity for understanding Kierkgaard, it shows him to be a writer of great interest to a secular as well as a religious audience. Evans' book brings Kierkegaard into conversation with western philosophers past and present, presenting him as one who gives powerful answers to the questions which philosophers ask. (shrink)

The term narcissism is normally used to describe an infatuation with the self so extreme that the interests of others are ignored. However, argues C. Fred Alford, psychoanalytic theory also implies that narcissism can be construed in a positive way, as a striving for perfection wholeness, and control over self and world. In this book, Alford applies the psychoanalytic theory of narcissism to the philosophies of Socrates and Frankfurt School members Max Horkheimer, Theodor Adorno, Herbert Marcuse, and Jurgen Habermas, contending (...) that it can illuminate basic philosophical issues such as the nature of the ideal society, the integrity of the self, and the role of reason in human affairs. (shrink)

Are there universal values of right and wrong, good and bad, shared by virtually every human? The tradition of natural law argues that there is. Drawing on the work of psychoanalyst Melanie Klein, whose analyses have touched upon issues related to original sin, trespass, guilt, and salvation through reparation, in this 2006 book C. Fred Alford adds an extra dimension to this argument: we know natural law to be true because we have hated before we have loved and have wished (...) to destroy before we have wanted to create. Natural law is built upon the desire to make reparation for the goodness we have destroyed, or have longed to destroy. Through reparation, we earn salvation from the most hateful part of ourselves, that which would destroy what we know to be good. (shrink)

In this paper I consider, in connection with dementia, two views of the person. One view of the person is derived from Locke and Parfit. This tends to regard the person solely in terms of psychological states and his/her connections. The second view of the person is derived from a variety of thinkers. I have called it the situated-embodied-agent view of the person. This view, I suggest, more readily squares with the reality of clinical experience. It regards the person as (...) embedded in a history and culture. The human person is also an embodied agent. I contend that this view encourages a more appropriate approach towards the ethical issues that arise in dementia and towards people with dementia. (shrink)

This paper argues that the concept and role of ‘institutional racism’ in contemporary discussions of race should be reconsidered. It starts by distinguishing between ‘intrinsic institutional racism’, which holds that institutions are racist in virtue of their constitutive features, and ‘extrinsic institutional racism’, which holds that institutions are racist in virtue of their negative effects. It accepts intrinsic institutional racism, but argues that a ‘disparate impact’ conception of extrinsic conception faces a number of objections, the most serious being that it (...) has no plausible account of what it is that makes extrinsically racist institutions racist. It also argues that claims about the explanatory indispensability of institutional racism are overstated (individual racism is at least as important), critiques structural approaches to racial inequality, and suggests that there is reason to doubt whether institutional reform can provide us with all that morality may require in the racial domain. (shrink)

Introduction -- Saint Thomas : putting nature into natural law -- Maritain and the love for the natural law -- The new natural law and evolutionary natural law -- International human rights, natural law, and Locke -- Conclusion : evil and the limits of the natural law.